Although efforts to develop an HIV vaccine are underway, recruiting and retaining key populations for a vaccine efficacy trial would be complicated by stigma and laws against prostitution and sex between men. This study simulates an HIV vaccine efficacy trial to test methods for recruiting and retaining high risk volunteers. The study is designed to look like an actual HIV vaccine trial, but a Hepatitis B vaccine (available and widely used in Kenya) is used instead of an HIV vaccine. PHDA identifies and refers volunteers, and the Kenya AIDS Vaccine Initiative screens, enrols, and follows up participants.
Funders: The International AIDS Vaccine Initiative and Kenya AIDS Vaccine Initiative